منابع مشابه
Widespread noncoding circular RNAs in plants.
A large number of noncoding circular RNAs (circRNAs) with regulatory potency have been identified in animals, but little attention has been given to plant circRNAs. We performed genome-wide identification of circRNAs in Oryza sativa and Arabidopsis thaliana using publically available RNA-Seq data, analyzed and compared features of plant and animal circRNAs. circRNAs (12037 and 6012) were identi...
متن کاملnoncoding rnas and cancer
the eukaryotic complexity involves the expression and regulation of genes via rna-dna, rna-rna, dna-protein and rna-protein interactions. recently, the role of rna molecules in the regulation of genes in higher organisms has become more evident, especially with the discovery that about 97% of the transcriptional output in higher organisms are represented as noncoding rnas: rrna, snornas, trna, ...
متن کاملCircular RNA: A new star of noncoding RNAs.
Circular RNAs (circRNAs) are a novel type of RNA that, unlike linear RNAs, form a covalently closed continuous loop and are highly represented in the eukaryotic transcriptome. Recent studies have discovered thousands of endogenous circRNAs in mammalian cells. CircRNAs are largely generated from exonic or intronic sequences, and reverse complementary sequences or RNA-binding proteins (RBPs) are ...
متن کاملPre-mRNA splicing: from protein-coding to noncoding RNAs.
Since I started in the pre-mRNA splicing field about three decades ago, I will beginn my little historical recollection at a somewhat earlier time than when the RNA journal started. To keep this somehow organized, I will summarize in decades, starting with the 1980s. What were significant changes in the RNA field over the past few decades? All of that from a very personal perspective. My own re...
متن کاملNoncoding RNAs
Recent years have witnessed many remarkable discoveries in the life sciences that have led to major paradigm shifts. An example is the emerging appreciation of the critical role of noncoding RNAs in a broad range of physiological and pathological processes. One such class of noncoding RNAs, the microRNAs (miRNAs), controls intricate networks of gene expression via post-transcriptional mechanism...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cell Research
سال: 2017
ISSN: 1001-0602,1748-7838
DOI: 10.1038/cr.2017.70